The PIVOT consortium collaborates with industry partners on preclinical testing of molecularly targeted agents developed for adult cancers to evaluate their applicability to the treatment of pediatric cancer.

The Pediatric Preclinical In Vivo Testing (PIVOT) consortium comprises a coordinating center and seven academic research programs specializing in basic research and preclinical testing of treatments for the most common pediatric cancers.  Our team has decades of experience with the development, characterization and testing of in vivo models of pediatric cancer. PIVOT is a public-private partnership funded by the National Cancer Institute (NCI).

PIVOT Consortium Members

Coordinating Center

Carol J. Bult, PhD
Jeff H. Chuang, PhD
Emily Jocoy, PhD
Dennis Dean, PhD

Sarcomas, Kidney, Liver

Peter J. Houghton, PhD
Raushan Kurmasheva, PhD


Yael Mossé, MD
John M. Maris, MD

Childhood Leukemia

Richard Lock, PhD

Brain Tumors

Xiao-Nan Li, MD, PhD


Richard G. Gorlick, MD

Soft Tissue Sarcomas

Michael A. Dyer, PhD
Elizabeth Stewart, MD
Sarcomas, Kidney, Rare Tumors
Andrew Kung, MD, PhD
Filemon Dela Cruz, MD